Page 126 - Microsoft Word -Cow Book 10-06-09 final update.doc

NOTE: The Nolvasan (chlorhexidine) Cap-Tabs (boluses) and the Nolvasan
Suspension (infusion tubes) for intrauterine treatments are no longer
labeled for use in cattle. They are approved for use in horses only. They
may be extra labeled by veterinarians.

E. Combination penicillin/streptomycin dihydrostreptomycin for
injection or feed use:

Procaine penicillin combined with streptomycin and\or dihydrostreptomycin
were removed from approval by FDA on November 19, 1992. Distribution
ceased on June 1, 1993. If found on dairy farms during regulatory
inspections or IMS ratings after the expiration date has passed, they are
in violation of Item 15r of the Ordinance (see M-I-92-14, Dec 7, 1992).
Intra-mammary infusion products containing the two drug combination are
currently still approved legal products.

F. DMSO:

DMSO (dimethylsulfoxide) is a by-product of the paper industry and
is able to carry some drugs rapidly through the skin and other
tissues. There are no FDA approved uses for DMSO in food-producing
animals. Approvals do exist for uses in horses and dogs.

Industrial grade DMSO is widely available for various non-medical uses
such as paint remover and other solvent uses. DMSO is often found
stored on dairy farms or mixed with other drugs intended for use in dairy
animals. Such uses may lead to an increased chance of drug residues, off
odor, and off flavor milk.

FDA considers the use of DMSO for any veterinary purposes other
than approved uses in dogs and horses to be illegal.

DMSO is an unapproved new animal drug which is unsafe with the
meaning of the Act. Such use causes the product to be adulterated
under section 501(a)(5) of the Federal Food, Drug and Cosmetic Act.

The use of DMSO on dairy animals or the storage of DMSO in dairy
farm drug cabinets violates item 15r of the PMO.

116